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Projects Sharing Researchers

Researchers

  • Suresh Mishra
  • Sudharsana Ande
  • Khanh Nguyen

Communicate

Details

Project TitleGenetically-induced obese mouse model for NASH and HCC
Track Code2016-030
Short Description

A mouse transgeinc line overexpressing Prohibitin in the liver and macrophages. This results in the spontaneous development of liver disease and liver cancer.

Abstract

This technology provides the only animal model for the spontaneous development of fatty liver disease progressing to liver cancer. It is based on tissue specific overexpression of the mitochondrial regulatory molecule prohibitin. As such, the mouse embodies a novel therapeutic target for obesity, liver disease and cancer.

 
Tagsresearch tools, diagnostics
 
Posted DateApr 11, 2016 4:43 PM

Researcher

Name
Suresh Mishra
Sudharsana Ande
Khanh Nguyen

Manager

Name
Odd Bres

One page summary

Inquiries

Odd Bres, Ph.D.

Technology Manager

Ph: +1(204)474.9407

Cell: +1(204)292.4238

Email: odd.bres@umanitoba.ca

Files

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Technology Transfer Office
631 Drake Centre, 181 Freedman Crescent,
University of Manitoba, Winnipeg, MB R3T 5V4 Canada
Office: 204.474.6200  Fax: 204.261-3475
tto@umanitoba.ca